Seth MacFarlane

Creator of Family Guy, American Dad, and The Cleveland Show.

Was nearly killed in the 9/11 terrorist attacks, when he didn't board Flight 11 (which crashed in the North Tower).

Film Deaths:

Ted (2012) [Ted]: Providing the voice of a CGI teddy bear, "Ted's" life-magic wears off after he gets torn in half by Giovanni Ribisi, with Mark Wahlberg and Mila Kunis by his side. He is brought back to life the next day after Mila wishes on a shooting star.

A Million Ways to Die in the West (2014) [Albert]: In a drug trip sequence, he's shot through the chest by a dwarf cowboy. (Seth survives the film in reality) (Played for comic effect.)

Family Guy (1999-present; animated) [Various Characters]: Providing multiple voices in every episode, many of his characters have died. (A comprehensive list would be almost impossible to compile.)

Robot Chicken (2005-present; animated) [Various Characters]: Providing multiple voices in numerous episodes, many of his characters have died. (A comprehensive list would be almost impossible to compile.)

American Dad: The Most Adequate Christmas Ever (2007; animated) [Stan Smith]: Crushed to death by a tree after he chops it down and it blows over on top of him, he is later brought back to life by God (Seth MacFarlane) after he shows him some humility.

American Dad: Rapture's Delight (2009; animated) [Stan Smith]: Shot in the chest by the Anti-Christ (Andy Samberg) after he dives in front of his bullet meant for Jesus (Will Forte), he later dies after talking to Jesus and Francine (Wendy Schaal), he is later seen in his version of heaven with the rest of his family.
American Dad: Hot Water (2011; animated) [Stan Smith]: Dies of his wounds after being thrown through the roof by the Hot Tub (CeeLo Green) trying to save Francine (Wendy Schaal).
Family Guy: Life of Brian (2013; animated) [Brian Griffin]: Dies of his wounds after being ran over and crushed by a speeding car. His death was later reversed in Christmas Guy. (I'm listing this 'death' as it was one of the main characters of the show).

Brother of Rachel MacFarlane.

distant Cousin of Denise Crosby.