Due to the nature of the narrative being controlled by the player, characters that are labeled with an asterisk mean that their deaths occur only when the player makes specific decisions during the game.
Actor Deaths
- Aidan Gillen (Paul Serene)
- Dominic Monaghan (William Joyce)
- Lance Reddick (Martin Hatch)
- Marshall Allman (Charlie Wincott)*
- Patrick Heusinger (Liam Burke)
Actress Deaths
- Courtney Hope (Beth Wilder)
- Jacqueline Pinol (Dr. Sofia Amaral)*
- Amelia Rose Blaire (Amy Ferraro)*