Director: Brad Bird
- Mike Dopud [Kremlin Subcellar Hallway Guard]
- Samuli Edelmann [Wistrom]
- Josh Holloway [Hanaway]
- Michael Nyqvist [Hendricks]
- Ivan Shvedoff [Leonid Lisenker]
- Tom Wilkinson [IMF Secretary]
- Léa Seydoux [Sabine Moreau]
- Brad Bird's live-action directorial debut.
- Twenty-five minutes of the film was shot in IMAX 70mm.
- Michael Giacchino is the first composer to score more than one movie of the franchise.
- Tom Cruise performed the sequence where Ethan Hunt scales the outside of the Burj Khalifa tower himself without the use of a stunt double. The Burj Khalifa tower is the tallest building in the world at 2,722 feet, or 829.8 meters. Cruise dangled outside the tower at approximately 1,700 feet, or 518 meters.
- Jeremy Renner was offered the role of Jackson Lamb in Super 8 (2011) (eventually taken by Kyle Chandler) but took the role of Brandt when J.J. Abrams told him that Tom Cruise and Brad Bird were interested in him. When accepting the role, Renner was only briefed on the film and character outline as there was no script at that point.
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