John Malkovich (1953 - )
- Dangerous Liaisons (1988) [Vicomte de Valmont]: Killed in a swordfight with Keanu Reeves. (Thanks to Marietha)
- The Sheltering Sky (1990) [Port Moresby]: Dies of a fever; Campbell Scott then buries his body in the desert. (Thanks to Nilescu)
- Of Mice and Men (1992) [Lennie Small]: Shot in the head by Gary Sinise (to spare him from an approaching lynch mob), after he makes John imagine a dream place.
- In the Line of Fire (1993) [Mitch Leary]: Falls out of a glass elevator after a struggle with Clint Eastwood (his body is later seen as Clint descends in the elevator).
- Heart of Darkness (1994) [Kurtz]: I haven't seen this movie, but I vaguely remember that Kurtz dies near the end of the book (though I can't recall the details).
- Mary Reilly (1996) [Dr. Henry Jekyll/Mr. Edward Hyde]: Dies of an overdose of his formula, as Julia Roberts helplessly listens to his heartbeat (his body is later seen as Julia wakes up next to him). (Thanks to Stephen)
- Con Air (1997) [Cyrus 'The Virus' Grissom]: Head crushed/decapitated by a pile driver at a construction site, when Nicolas Cage handcuffs John to the ladder during a scuffle on a fire truck, sends him flying through an overhead walkway, onto some power lines, and finally landing in the pile driver.
- Being John Malkovich (1999) [John Horatio Malkovich]: His mind is destroyed when Orson Bean and his followers enter the portal into his brain.
- Les Miserables (2000) [Javert]: Commits suicide by drowning himself in the river. (Thanks to Hamish)
- Knockaround Guys (2001) [Teddy Deserve]: Killed by Barry Pepper. (Thanks to Gary)
- Johnny English (2003) [Pascal Savage]: After his arrest by London Police and being locked away under Rowan Atkinson's orders, his sentence with death is debatable, but rarely mentioned by anyone. (Played for comic effect.)
- Burn After Reading (2008) [Osbourne Cox]: Presumbably dies (off-screen) after being shot in the head (also off-screen) by a CIA agent; it's stated in the closing conversation between David Rasche and J.K. Simmons that John is in a coma and is not expected to survive. (Thanks to John, ND, and Tommy)
- Mutant Chronicles (2008) [Constantine]: Killed (off-screen) by mutants after being cornered in his office, we only see them moving towards him.
- Jonah Hex (2010) [Quentin Turnbull]: Killed in an explosion after his head gets trapped in a gear at the end of a fight with Josh Brolin.