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Alfred Molina (1953 - )
- Raiders of the Lost Ark (1981) [Satipo]: Impaled (off-screen) by several spikes that shoot out of the wall when he tries to escape from the temple; his body is shown afterwards when Harrison Ford discovers him.
- Ladyhawke (1985) [Cezar]: Neck caught in a wolf trap.
- Prick Up Your Ears (1987) [Kenneth Halliwell]: Commits suicide by taking an overdose of sleeping pills after he beats Gary Oldman to death in their bedroom; the movie opens with a close-up of Alfred's groggy face before he loses consciousness, and the rest of the movie shows the events leading up to the murder/suicide. Alfred's body is shown lying on the floor at the end of the movie.
- Hancock (1991) [Tony Hancock]: Commits suicide by drug overdose.
- Maverick (1994) [Angel]: Shot to death in a shoot-out between his gang and Mel Gibson and James Garner.
- White Fang 2: Myth of the White Wolf (1994) [Reverend Leland Drury]: Trampled to death by elk herds after being knocked off a horse-drawn carriage by Scott Bairstow's timber wolf.
- Dead Man (1995) [Trading Post Missionary]: Shot in the chest by Johnny Depp at the trading post, after Alfred pulls his own gun and Johnny stabs him in the hand.
- Hideaway (1995) [Dr. Jonas Nybern]: Stabbed by Jeremy Sisto; he dies some time afterwards while talking to Jeff Goldblum.
- Species (1995) [Dr. Stephen Arden]: Mauled to death by Natasha Henstridge after she assumes her alien form after having sex with him in his hotel room.
- Texas Rangers (2001) [John King Fisher]: Shot to death by James Van Der Beek just as Alfred is about to kill Dylan McDermott.
- Identity (2003) [Dr. Malick]: Strangled to death by Pruitt Taylor Vince when Pruitt suddenly lunges at him after opening a divider on a transport van going to a mental hospital.
- Spider-Man 2 (2004) [Dr. Otto Octavius a.k.a. Doctor Octopus]: Drowned when he pulls his fusion reactor into the river to stop it. His body is shown floating in the water afterwards. (He will appear in a upcoming film, Spider Man: No Way Home in a same role despite his character's death in Original film)
- Wonder Woman (2009; animated) [Ares]: Decapitated by Wonder Woman (voiced by Keri Russell) after a sword duel.
- Message From The King (2016) [Mike Preston]: Shot in the head by Chadwick Boseman after he finds a video of Molina molesting Boseman's nephew.
- Justice League Dark (2017; animated) [Destiny]: His body is destroy when Batman(voiced by Jason O' Mara), John Constantine (voiced by Matt Ryan), and Jason Blood (voiced by Ray Chase) destroy the Dreamstone.
- Don't Let Go (2019) [Howard]: Shot in the head by Mykelti Williamson as David Oyelowo watch on in horror. (His death may be erased after past David shot Mykelti but his fate wasn't confirm)
- Frozen 2 (2019; animated) [Agnarr]: Drowns with Evan Rachel Wood (Iduna) when their ship sinks in a storm. He appears in visions and flashback sequences throughout the film. (NOTE: Maurice LaMarche voiced the character in Frozen (2013). However, since Molina voices him in this film and the subject of his death is revisited, this entry counts as well.)
- Show Me a Hero (2015 mini-series) [Hank Spallone]: The text at the end of the series informs us that he died some time after the events depicted on the show. (Along with Catherine Keener, Peter Riegert and LaTanya Richardson Jackson).
- Hey Arnold: The Jungle Movie (2017; animated) [La Sombra]: Injected with a poison by a sacred statue that senses his evil intent, he succumbs to the poison after attempting to kill Arnold (Mason Vale Cotton), resulting himself to fall off a cliff.
- Dragons: Race to the Edge: Triple Cross (2018) [Viggo Grimborn]: Sacrifices himself as he charges after the Dragon Hunters as the Skrill dragon sends off its attack in order to save Hiccup (voiced by Jay Baruchel).
- Harley Quinn: Thawing Hearts (2020) [Victor Fries/Mr. Freeze]: Sacrifices his life by injecting Poison Ivy's (Lake Bell) antidote into himself and having his blood transfused into his wife Nora (Rachel Dratch) so that she will recover from her disease.
- Solar Opposites: The Unlikely Demise of Terry's Favorite Shot Glass (2021; animated) [The Duke]: Playing someone who has been shrunk down, he is fatally injured in an explosion after sacrificing himself to save Christina Hendricks from an opossum by blowing it up with a firecracker.
Video Game Deaths
- Spider-Man 2 (2004) [Dr. Otto Octavius a.k.a. Doctor Octopus]: Crushed to death or drowns when he tears apart the building to stop the fusion reactor from destroying New York.
- Mr. Jill Gascoine (widowed)
- Mr. Jennifer Lee (filmmaker)